LL-37
The only human cathelicidin—a host-defense peptide with antimicrobial and immune-modulating roles in the gut and skin.
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✨ real molecule sketch
On a prescription or label?
Human antimicrobial peptide
GLP-1 medicines and gut peptides have distinct names—brand names, generics, and research codes.
Structure (cute edition)
✨ real molecule sketch
This peptide is a short chain of about 4 amino acids—think of it as a tiny protein necklace on your label.
INCI: Human antimicrobial peptide · ~4 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
PubMed: 3073 indexed papers (search PubMed)
- Corrigendum to "Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF-κB signaling pathway" [Int. Immunopharmacol. 129 (2024) 111636]. · International immunopharmacology
- In Vivo Activity of Antimicrobial Peptoid Oligomers against HSV-1 in a Mouse Model of Herpes Labialis. · ACS infectious diseases
- Vitamin D receptor BsmI haplotype BB confers lower 25(OH)D levels during tuberculosis: a pilot cross-sectional study. · Therapeutic advances in infectious disease
- Interaction between vitamin D insufficiency and periodontitis, GCF vitamin D and LL-37 levels in well-controlled diabetes patients with periodontitis. · European oral research
- LL-37 inhibits osteosarcoma progression by suppressing SQLE-mediated cholesterol synthesis via the PTEN/AKT/mTOR pathway. · Journal of bone oncology
- The potential role of H(2)S in the anti-infective function of antimicrobial peptides. · Nature communications
- Corrigendum to "Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF-κB signaling pathway" [Int. Immunopharmacol. 129 (2024) 111636]. · International immunopharmacology
- Antimicrobial peptoids pass rapidly through bacterial membranes and flocculate ribosomes and DNA: A single-cell fluorescence study. · Proceedings of the National Academy of Sciences of the United States of America
Clinical trials: 191 studies on ClinicalTrials.gov (view search)
- Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid · NOT_YET_RECRUITING
- Nutritional Intervention and Respiratory Infections in Older Subjects · UNKNOWN
- Rapid Normalization of Vitamin D in Critically Ill Children: A Phase II Dose Evaluation Randomized Controlled Trial · COMPLETED
- Peri-implant Vitamin D and Cathelicidin (LL-37) Levels · COMPLETED
- The Assessment of Antimicrobial Peptides Against Fungal Infection · UNKNOWN
- Effect of Pimecrolimus Cream on Cathelicidin Levels in Subjects With Eczema · COMPLETED
- Air Pollution and Inhaled Corticosteroids in COPD · NOT_YET_RECRUITING
- Nutrition, Immunity, and Covid-19 in Obese People · COMPLETED
ChEMBL: CHEMBL2074774
What brands say it does
LL-37 kills bacteria and modulates inflammation at mucosal surfaces. Low levels are linked to dysbiosis and psoriasis. Research explores it for IBD and wound healing. Not available as a consumer product; studied in academic and clinical trials.
Where you’ll find it
Immunology research, microbiome studies—not retail supplements.
Other names you might see
Cathelicidin
Human antimicrobial peptide
hCAP18 fragment
Similar peptides
Educational only—not medical advice. GLP-1 drugs require a prescription; do not source medications online without a clinician.