GLP-1 agonist peptides
Plain-English guides to 4 peptides used for glp-1 agonist in gut and metabolic health.
Exenatide
GLP-1 agonist
The first approved GLP-1 mimetic—derived from Gila monster saliva peptide exendin-4.
On label: Exenatide
Liraglutide
GLP-1 agonist
An earlier daily-injection GLP-1 agonist—still used for diabetes and weight loss.
On label: Liraglutide
Retatrutide
GLP-1 agonist
A once-weekly GLP-1/GIP/glucagon receptor triple agonist in late-stage trials for obesity—next-gen metabolic peptide drug.
On label: Retatrutide
Semaglutide
GLP-1 agonist
A GLP-1 receptor agonist peptide drug approved for type 2 diabetes and chronic weight management.
On label: Semaglutide